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June 2025

Knockout Mouse
“Cancer is extremely varied and adaptive, and is likely the hardest of these diseases to fully destroy.” — Dario Amodei
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Brain Freeze
The idea of cryonics — freezing the bodies of the dead in the hopes that they can one day be revived — has existed since the 1960s. We’ve since learned…
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The Origin of the Research University
Universities have existed for more than a thousand years — and for almost all of that time, they weren’t centers of research. What changed in 19th…
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The Universal Tech Tree
When we try and pick out any technology in isolation, we find it hitched, in some way, to every innovation that preceded it. (Except for the Oldowan…
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May 2025

What Are Schools For?
The modern education system around the world continues to bear the imprint of mass education’s original goal: obedience.
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Can We Trust Social Science Yet?
Everyone likes the idea of evidence-based policy, but it’s hard to realize it when our most reputable social science journals are still publishing poor…
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Forecast Series: The Mortality Impacts of USAID Cuts
A special series of five forecasts on the Trump Administration's cuts to some of USAID's most effective programs.
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Forecast: The Impact of USAID Malaria Cuts
by Bruce Tsai
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Forecast: The Impact of USAID Nutrition Cuts
by Anna Gordon & Lauren Gilbert
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Forecast: The Impact of USAID WASH Cuts
by Erin Braid
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Forecast: The Impact of USAID Tuberculosis Cuts
by Kati Conen
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